Kev txhim kho thiab kev siv optics tau pab cov tshuaj niaj hnub thiab kev tshawb fawb txog lub neej nkag mus rau theem ntawm kev loj hlob sai, xws li kev phais me me, kev kho laser, kev kuaj kab mob, kev tshawb fawb lom neeg, kev tshawb xyuas DNA, thiab lwm yam.

Kev phais thiab Pharmacokinetics

Lub luag haujlwm ntawm optics hauv kev phais thiab pharmacokinetics feem ntau tshwm sim hauv ob yam: laser thiab hauv vivo illumination thiab duab.

1. Daim ntawv thov ntawm laser ua lub zog

Lub tswv yim ntawm kev kho laser tau qhia rau hauv qhov muag phais hauv xyoo 1960. Thaum ntau hom lasers thiab lawv cov khoom tau lees paub, kev kho laser tau nthuav dav mus rau lwm qhov chaw.

Lub teeb laser sib txawv (gas, khoom, thiab lwm yam) tuaj yeem emit pulsed lasers (Pulsed Lasers) thiab nruam lasers (Nruam nthwv dej), uas muaj qhov sib txawv ntawm cov ntaub so ntswg ntawm tib neeg lub cev. Cov teeb pom kev zoo no feem ntau suav nrog: pulsed ruby ​​​​ laser (Pulsed ruby ​​​​ laser); nruam argon ion laser (CW argon ion laser); nruam carbon dioxide laser (CW CO2); yttrium aluminium garnet (Nd:YAG) laser. Vim tas li carbon dioxide laser thiab yttrium aluminium garnet laser muaj cov nyhuv coagulation thaum txiav tib neeg cov ntaub so ntswg, lawv tau siv dav hauv kev phais.

Lub wavelength ntawm lasers siv nyob rau hauv kev kho mob yog feem ntau ntau dua 100 nm. Kev nqus ntawm lasers ntawm txawv wavelengths nyob rau hauv cov ntaub so ntswg sib txawv ntawm tib neeg lub cev yog siv los nthuav nws daim ntawv thov kev kho mob. Piv txwv li, thaum lub wavelength ntawm lub laser ntau dua 1um, dej yog thawj absorber. Lasers tuaj yeem tsis tsuas yog tsim cov teebmeem thermal hauv tib neeg cov ntaub so ntswg nqus rau kev phais txiav thiab coagulation, tab sis kuj tsim cov teebmeem.

Tshwj xeeb tshaj yog tom qab cov neeg nrhiav pom qhov tsis zoo ntawm cov tshuab lasers, xws li tiam ntawm cavitation npuas thiab siab tsis, lasers tau siv rau cov txheej txheem photodisruption, xws li kev phais mob cataract thiab lub raum pob zeb crushing tshuaj phais. Lasers tseem tuaj yeem tsim cov teebmeem photochemical los coj cov tshuaj mob qog noj ntshav nrog cov kws khomob photosensitive los tso tawm cov teebmeem tshuaj ntawm cov nqaij mos tshwj xeeb, xws li kev kho PDT. Laser ua ke nrog pharmacokinetics plays lub luag haujlwm tseem ceeb hauv thaj chaw ntawm cov tshuaj precision.

2. Kev siv lub teeb ua ib qho cuab yeej rau hauv vivo illumination thiab duab

Txij li xyoo 1990, CCD (Chaw-CoupledNtaus) lub koob yees duab tau nkag mus rau hauv kev phais me me (Minimally Invasive Therapy, MIT), thiab optics tau hloov pauv zoo hauv daim ntawv thov phais. Cov duab los ntawm lub teeb nyob rau hauv minimally invasive thiab qhib phais feem ntau suav nrog endoscopes, micro-imaging systems, thiab phais holographic imaging.

Yooj yimEndoscope, suav nrog gastroenteroscope, duodenoscope, colonoscope, angioscope, thiab lwm yam.

Txoj kev kho qhov muag ntawm endoscope

Txoj kev kho qhov muag ntawm qhov endoscope suav nrog ob txoj kev ywj pheej thiab kev sib koom ua ke ntawm kev teeb pom kev zoo thiab kev kos duab.

RiamEndoscope, suav nrog arthroscopy, laparoscopy, thoracoscopy, ventriculoscopy, hysteroscopy, cystoscopy, otolinoscopy, thiab lwm yam.

Rigid endoscopes feem ntau tsuas yog muaj ob peb txoj kev kho qhov muag kom xaiv los ntawm, xws li 30 degrees, 45 degrees, 60 degrees, thiab lwm yam.

Lub koob yees duab lub cev me me yog ib qho khoom siv duab raws li qhov me me CMOS thiab CCD thev naus laus zis platform. Piv txwv li, capsule endoscope,PillCam. Nws tuaj yeem nkag mus rau hauv lub plab zom mov ntawm tib neeg lub cev los kuaj xyuas qhov mob thiab saib xyuas cov teebmeem ntawm cov tshuaj.

Capsule endoscope

Kev phais holographic microscope, ib qho cuab yeej siv los soj ntsuam 3D cov duab ntawm cov ntaub so ntswg zoo hauv kev phais mob, xws li neurosurgery rau craniotomy.

Kev phais holographic microscope

Saum toj no:

1. Vim tias cov nyhuv thermal, cov nyhuv mechanical, cov nyhuv photosensitivity thiab lwm yam teebmeem ntawm lub laser, nws yog dav siv los ua lub zog hauv kev phais me me, kev kho mob uas tsis muaj kev cuam tshuam thiab kev siv tshuaj kho mob.

2. Vim yog txoj kev loj hlob ntawm cov cuab yeej siv tshuab, cov cuab yeej kho qhov muag kho qhov muag tau ua tau zoo nyob rau hauv cov kev taw qhia ntawm kev daws teeb meem siab thiab miniaturization, nteg lub hauv paus rau minimally invasive thiab meej phais hauv vivo. Tam sim no, cov khoom siv kho mob uas siv ntau tshaj plaws suav nrogendoscopes, holographic dluab thiab micro-imaging systems.