Nts'etsopele le ts'ebeliso ea li-optics li thusitse meriana ea sejoale-joale le mahlale a bophelo ho kena mothating oa nts'etsopele e potlakileng, joalo ka ho buuoa ka mokhoa o fokolang, kalafo ea laser, tlhahlobo ea mafu, lipatlisiso tsa baeloji, tlhahlobo ea DNA, jj.

Opereishene le Pharmacokinetics

Karolo ea optics ho opereishene le pharmacokinetics e bonahala haholo-holo ka likarolo tse peli: khanya ea laser le in vivo le imaging.

1. Tšebeliso ea laser e le mohloli oa matla

Khopolo ea phekolo ea laser e ile ea kenngoa tšebetsong ea ho buuoa ka mahlo lilemong tsa bo-1960. Ha mefuta e fapaneng ea li-laser le thepa ea tsona e lemohuoa, kalafo ea laser e ile ea atolosetsoa mafapheng a mang ka potlako.

Mehloli e fapaneng ea lebone la laser (khase, e tiileng, joalo-joalo) e ka ntša li-lasers tsa pulsed (Pulsed Lasers) le li-lasers tse tsoelang pele (Leqhubu le tsoelang pele), tse nang le litlamorao tse fapaneng liseleng tse fapaneng tsa 'mele oa motho. Mehloli ena ea leseli haholo-holo e kenyelletsa: laser ea pulsed ruby ​​​​(Pulsed ruby ​​​​laser); laser argon ion laser (CW argon ion laser); carbon dioxide laser e tsoelang pele (CW CO2); yttrium aluminium garnet (Nd:YAG) laser. Hobane laser ea carbon dioxide e tsoelang pele le yttrium aluminium garnet laser e na le phello ea ho kopanya mali ha ho seha lisele tsa motho, li sebelisoa haholo ho buuoa ka kakaretso.

Bophahamo ba maqhubu a laser a sebelisoang kalafong ea bongaka hangata bo boholo ho feta 100 nm. Ho monya ha lasers tsa wavelengths tse fapaneng liseleng tse fapaneng tsa 'mele oa motho ho sebelisoa ho holisa lits'ebetso tsa ona tsa bongaka. Ka mohlala, ha leqhubu la leqhubu la laser le le leholo ho feta 1um, metsi ke oona o monyang ka sehloohong. Li-Lasers ha li khone ho hlahisa feela litlamorao tsa mocheso ho monyeng ha lisele tsa motho bakeng sa ho itšeha le ho kopanya, empa hape li hlahisa litlamorao tsa mochini.

Haholo-holo ka mor'a hore batho ba sibolle liphello tse sa tloaelehang tsa lisebelisoa tsa laser, tse kang ho hlahisa li-bubble tsa cavitation le maqhubu a khatello, li-lasers li ile tsa sebelisoa ho mekhoa ea photodisruption, e kang opereishene ea cataract le opereishene ea liphio ea ho senya lik'hemik'hale. Li-Lasers li ka boela tsa hlahisa litlamorao tsa photochemical ho tataisa lithethefatsi tsa mofets'e tse nang le li-photosensitive mediators ho lokolla litlamorao tsa lithethefatsi libakeng tse itseng, joalo ka kalafo ea PDT. Laser e kopantsoeng le pharmacokinetics e phetha karolo ea bohlokoa haholo lefapheng la meriana e nepahetseng.

2. Tšebeliso ea leseli e le sesebelisoa sa ho bonesa le ho etsa litšoantšo ka har'a vivo

Ho tloha lilemong tsa bo-1990, CCD (Charge-CoupledSesebelisoa) khamera e ile ea kenngoa ts'ebetsong e fokolang haholo (Minimally Invasive Therapy, MIT), 'me optics e bile le phetoho ea boleng lits'ebetsong tsa ho buoa. Litlamorao tsa ho nahana ha leseli nakong ea opereishene e sa hlaseleng habonolo le e bulehileng haholo li kenyelletsa li-endoscopes, li-micro-imaging system, le imaging ea holographic ea opereishene.

E tenyetsehangEndoscopeho kenyelletsa gastroenteroscope, duodenoscope, colonoscope, angioscope, joalo-joalo.

Tsela ea optical ea endoscope

Tsela ea optical ea endoscope e kenyelletsa mekhoa e 'meli e ikemetseng le e hokahaneng ea ho bonesa le ho nka litšoantšo.

E thatafetseEndoscope, ho kenyelletsa arthroscopy, laparoscopy, thoracoscopy, ventriculoscopy, hysteroscopy, cystoscopy, otolinoscopy, joalo-joalo.

Li-endoscope tse thata ka kakaretso li na le li-angles tse 'maloa tse tsitsitseng tsa optical tseo u ka khethang ho tsona, joalo ka likhato tse 30, likhato tse 45, likhato tse 60, jj.

Khamera e nyane ea 'mele ke sesebelisoa sa ho nka litšoantšo se ipapisitseng le sethala sa theknoloji sa CMOS le CCD. Ka mohlala, endoscope ea capsule.PillCam. E ka kena tsamaisong ea tšilo ea lijo ea 'mele oa motho ho hlahloba liso le ho beha leihlo liphello tsa lithethefatsi.

Endoscope ea capsule

Holographic microscope ea ho buoa, sesebelisoa sa ho nka litšoantšo se sebelisetsoang ho bona litšoantšo tsa 3D tsa lisele tse ntle ka ho buoa ka nepo, joalo ka neurosurgery bakeng sa craniotomy.

Holographic microscope ea opereishene

Akaretsa:

1. Ka lebaka la phello ea mocheso, phello ea mochine, phello ea photosensitivity le liphello tse ling tsa likokoana-hloko tsa laser, e sebelisoa haholo e le mohloli oa matla ho buuoang ka mokhoa o fokolang, phekolo e sa tsitsang le phekolo ea lithethefatsi e lebisitsoeng.

2. Ka lebaka la tsoelo-pele ea theknoloji ea litšoantšo, lisebelisoa tsa bongaka tsa optical imaging li entse tsoelo-pele e kholo mabapi le qeto e phahameng le miniaturization, ho rala motheo oa ho buuoa ka mokhoa o fokolang le o nepahetseng ka vivo. Hona joale, lisebelisoa tsa litšoantšo tsa bongaka tse sebelisoang ka ho fetisisa li kenyelletsali-endoscopes, litšoantšo tsa holographic le micro-imaging systems.