ʻO ka hoʻomohala ʻana a me ka hoʻohana ʻana i nā optics ua kōkua i ka lāʻau lapaʻau hou a me ka ʻepekema ola e komo i kahi pae o ka hoʻomohala wikiwiki, e like me ka hōʻoki ʻana i ka liʻiliʻi, ka laser therapy, ka maʻi maʻi, ka noiʻi biological, DNA analysis, etc.

ʻO ka ʻoki a me nā Pharmacokinetics

ʻO ka hana o nā optics i ka ʻokiʻoki a me nā pharmacokinetics i hōʻike nui ʻia ma nā ʻano ʻelua: laser a me in vivo illumination a me imaging.

1. Ke noi ʻana i ka laser e like me ke kumu ikehu

Ua hoʻokomo ʻia ka manaʻo o ka lāʻau lapaʻau laser i ka ʻoki ʻana i ka maka i ka makahiki 1960. I ka ʻike ʻia ʻana o nā ʻano like ʻole o ka laser a me ko lākou mau waiwai, ua hoʻonui koke ʻia ka lāʻau lapaʻau laser i nā kula ʻē aʻe.

Hiki i nā kumu kukui laser ʻokoʻa (gas, solid, etc.) ke hoʻokuʻu i nā laser pulsed (Pulsed Lasers) a me nā laser mau (Continuous wave), he mau hopena like ʻole ma nā ʻāpana like ʻole o ke kino kanaka. ʻO kēia mau kumu māmā ka mea nui: pulsed ruby ​​​​laser (Pulsed ruby ​​​​laser); laser argon ion mau (CW argon ion laser); laser carbon dioxide mau (CW CO2); yttrium alumini garnet (Nd:YAG) laser. Ma muli o ka hoʻomau ʻana o ka carbon dioxide laser a me ka yttrium alumini garnet laser i ka hopena coagulation koko i ka wā e ʻoki ai i ka ʻiʻo o ke kanaka, hoʻohana nui ʻia lākou i ke ʻoki ākea.

ʻOi aku ka nui o ka nalu o nā lasers i hoʻohana ʻia i ka lāʻau lapaʻau ma mua o 100 nm. Hoʻohana ʻia ka absorption o nā lasers o nā lōʻihi nalu like ʻole i nā ʻiʻo like ʻole o ke kino kanaka e hoʻonui i kāna mau lāʻau lapaʻau. No ka laʻana, inā ʻoi aku ka lōʻihi o ka hawewe o ka laser ma mua o 1um, ʻo ka wai ka mea hoʻopili mua. ʻAʻole hiki i nā lasers ke hana wale i nā hopena wela i ka absorption o ke kino kanaka no ka ʻoki ʻoki a me ka coagulation, akā hana pū kekahi i nā hopena mechanical.

Ma hope o ka ʻike ʻana o ka poʻe i nā hopena mechanical nonlinear o nā lasers, e like me ka hoʻokumu ʻana o nā ʻōpū cavitation a me nā nalu kaomi, ua hoʻohana ʻia nā lasers i nā ʻenehana hoʻoneʻe kiʻi, e like me ke ʻoki cataract a me ka ʻoki kino ʻana i ka pōhaku ʻāʻī. Hiki i nā lasers ke hana i nā hopena photochemical e alakaʻi i nā lāʻau maʻi kanesa me nā mea mediators photosensitive e hoʻokuʻu i nā hopena lāʻau ma nā wahi kiko kiko, e like me ka PDT therapy. ʻO ka laser i hui pū ʻia me nā pharmacokinetics he hana koʻikoʻi loa ia ma ke kahua o ka lāʻau lapaʻau pololei.

2. ʻO ka hoʻohana ʻana i ke kukui ma ke ʻano he mea hana no ka hoʻomālamalama in vivo a me ke kiʻi

Mai ka makahiki 1990, CCD (Charge-CoupledUa hoʻokomo ʻia ka pahupaʻi kiʻi i loko o ka hōʻoki liʻiliʻi invasive (Minimally Invasive Therapy, MIT), a ua loaʻa i nā optics kahi hoʻololi qualitative i nā noi ʻoki. ʻO nā hopena kiʻi kiʻi o ka mālamalama i ka liʻiliʻi invasive a me ka wehe ʻana i ka nui o nā endoscopes, nā ʻōnaehana micro-imaging, a me ke kiʻi holographic ʻokiʻoki.

ʻoluʻoluEndoscope, me ka gastroenteroscope, duodenoscope, colonoscope, angioscope, etc.

ʻO ke ala optical o ka endoscope

ʻO ke ala optical o ka endoscope e loaʻa i ʻelua ʻōnaehana kūʻokoʻa a hoʻonohonoho ʻia o ka mālamalama a me ke kiʻi.

ʻoʻoleʻaEndoscope, me ka arthroscopy, laparoscopy, thoracoscopy, ventriculoscopy, hysteroscopy, cystoscopy, otolinoscopy, etc.

Loaʻa i nā endoscopes koʻikoʻi he mau kihi ala optical paʻa e koho ai, e like me 30 degere, 45 degere, 60 degere, etc.

ʻO kahi kāmeʻa kino liʻiliʻi he mea kiʻi kiʻi i hoʻokumu ʻia ma kahi CMOS liʻiliʻi a me ka ʻenehana ʻenehana CCD. No ka laʻana, he capsule endoscope,PillCam. Hiki iā ia ke komo i loko o ka digestive system o ke kino o ke kanaka e nānā i nā ʻeha a nānā i nā hopena o nā lāʻau lapaʻau.

ʻO ka endoscope capsule

ʻO ka ʻokiʻoki holographic microscope, he mea hana kiʻi i hoʻohana ʻia no ka nānā ʻana i nā kiʻi 3D o ka ʻiʻo maikaʻi i ke ʻoki pololei, e like me ka neurosurgery no ka craniotomy.

ʻO ka microscope holographic ʻokiʻoki

Hōʻuluʻulu:

1. Ma muli o ka hopena wela, ka hopena mechanical, ka hopena photosensitivity a me nā hopena olaola ʻē aʻe o ka laser, ua hoʻohana nui ʻia ia ma ke ʻano he kumu ikehu i ka hōʻoki liʻiliʻi invasive, ka mālama non-invasive a me ka lāʻau lapaʻau i kuhikuhi ʻia.

2. Ma muli o ka hoʻomohala ʻana o ka ʻenehana kiʻi kiʻi, ua holomua nui nā mea hana imaging lāʻau lapaʻau i ke ala o ka hoʻonā kiʻekiʻe a me ka miniaturization, e kau ana i ke kumu no ka liʻiliʻi invasive a me ka pololei o ka ʻoki ʻana i vivo. I kēia manawa, ua hoʻohana ʻia nā mea hoʻohana maʻamau imagingendoscopes, nā kiʻi holographic a me nā ʻōnaehana micro-imaging.